Klazomenai, which is known as a motherland of the famous thinker Anaxagoras and is one of the 12 cities of the Ionia Confederation, cannot be dated. However it is true that, the city which is said to have been established by the Kolophons in the spot of today's light. Iskele had moved to an island nearby (Karantina Island) at the time of the lonian Revolt to escape from the Persian threat. According to the historians Pliny and Pausanias, afterwards Alexander the Great built a road connecting this island to the land. An independent city during the Roman period Klazomenai was known as an important trade centre.